UTMB ADVANCED PATHOPHYSIOLOGY 5355 Exam 3 with complete solutions
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Course
Pathophysiology
Institution
Pathophysiology
Biogenic Amine Theory linked to depression
Deficiency of neurotransmitters in brain of norepinephrine, dopamine, and/or serotonin. Particularly, a decrease in receptor binding with serotonin.
Neurotransmitter Receptor Hypothesis linked to depression
A deficiency of monoamine neurotransmitt...
UTMB ADVANCED PATHOPHYSIOLOGY
5355 Exam 3 with complete solutions
Biogenic Amine Theory linked to depression - ANSWER- Deficiency of
neurotransmitters in brain of norepinephrine, dopamine, and/or serotonin.
Particularly, a decrease in receptor binding with serotonin.
Neurotransmitter Receptor Hypothesis linked to depression - ANSWER- A
deficiency of monoamine neurotransmitters at neuronal synapses.
Antidepressants increase - ANSWER- Neuronal synaptic levels of monoamine
neurotransmitters.
if you have more receptors than neurotransmitters - ANSWER- Neurotransmitters
do not have time to re-charge thus, they do not function properly.
Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation - ANSWER- HPA
system dysregulation with excessive glucocorticoid secretion is found in a large
percentage of people suffering from major depression.
Patho of Alzheimer's includes - plaque formation, presence of --, with decreased
levels of - - ANSWER- Amyloid B, neurofibrillary tangles, acetylcholine these
disrupt impulse transmission
neurofibrillary tangles - ANSWER- are a deformation of the structure that carries
nutrients to neurons of the brain.
Decreased levels of choline acetyl transferase and acetylcholine is associated
with - ANSWER- Memory loss
Most common cause of dementia - ANSWER- Alzheimer's disease fatal 5-10 years
, Characteristics of Alzheimer's - ANSWER- Loss of memory, language , inability to
learn new things, dysfunction, delusions, cannot perform ADLs, majorly effects
social life
Parkinson's Disease is - ANSWER- Chronic motor progressive neuro-
degenerative known as a shaking palsy
Parkinson's disease is associated with - ANSWER- basal ganglia dysfunction and
atrophy of neurons in the substantia nigra that produce dopamine;
Characteristics of Parkinson's disease - ANSWER- Tremors at rest, rigidity,
bradykinesia, muscular rigidity and postural abnormalities.
2 Main Categories of CVA - ANSWER- Hemorrhagic and Ischemic
Subarachnoid hemorrhage - ANSWER- Bleeding into the subarachnoid space,
caused by trauma, aneurysm rupture presents as "worst headache of life".
surgical emergency
Ischemic CVA - ANSWER- reduction in cerebral blood flow results in hypoxia and
irreversible cell death with associated cerebral edema
3 types of ischemic CVA - ANSWER- thrombotic, embolic, hypercoagulable
states.
Thrombotic - ANSWER- caused by atherosclerosis blocking vessels. obstruction
of blood vessel due to localized occlusive process
Embolic - ANSWER- caused by blood clot, fat or air embolus traveling from
distant site to brain
Hypercoaguable state - ANSWER- conditions such as sickle cell disease,
polycythemia causing blood clot to form and obstruct vessel
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