decreased diastolic BP
- beta2 = dilation of skeletal muscle blood vessel
Phenylephrine receptors - answer✔✔alpha 1
Phenylephrine dose - answer✔✔40-200 mcg/min
Phenylephrine effects - answer✔✔vasoconstriction, and reflex bradycardia
Milrinone mechanism of action - answer✔✔Inhibits PDE-3 → ↑cAMP
↑ cAMP in heart: ↑[Ca]cytosol → inotropic
↑ cAMP in blood vessels: ↑Ca reuptake by sarcoplasmic reticulum → vasodilation
Epinephrine mechanism of action - answer✔✔Direct-acting alpha and beta agonist. Alpha:
vasoconstriction. Beta-1: positive inotropic, chronotropic, and dromotropic effects. Beta-2:
bronchial smooth muscle relaxation and dilation of skeletal vasculature. Blocks histamine
receptors.
milrinone - answer✔✔phosphodiesterase inhibitor
Septal leads and artery - answer✔✔V1, V2, - LM
Inferior leads and artery - answer✔✔II, III, aVF
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