treatment of obesity: evaluation of phentermine/topiramate - ANSWER Schedule IV drug indicated for chronic weight loss. Phetermine suppresses appetite which topirmate increses satiety. Most common side efrects are dry mouth, constipation, blurred vision, and numbness tingling.
-serious effects a...
treatment of obesity: evaluation of phentermine/topiramate - ANSWER Schedule IV drug indicated
for chronic weight loss. Phetermine suppresses appetite which topirmate increses satiety. Most
common side efrects are dry mouth, constipation, blurred vision, and numbness tingling.
-serious effects are memory loss, concentration, HTN, tachycardia, hypoglycemia
treatment of obesity: evaluation of phentermine/topiramate contraindications: - ANSWER Glaucoma
or hyperthyroid
-Should not be given with MAOI. Stop MAOI 2 weeks before starting.
-Carbonic anhydrase increases risk for metabolic acidosis
-diuretics that are not K+ sparing increases risk for hyperkalemia
Orlistat (Xenical) - ANSWER - Is prescribed to morbidly obese pts to lose weight. It prevents
absorption of some of the fat in the pts diet.
- The med should be taken 3 times/day within 1 hour of a meal
- Its a lipase inhibitor, not an appetite suppressor.
Orlistat (Xenical) adverse effects: - ANSWER Oily rectal leakage, sharting, fecal urgency, and fatty or
oily stools
-increased defecation and incontinence
-rare: severe liver damage —> itching, vomiting, anoxeria, dark urine, light colored stools
-acute pancreatitis and kidney stones
Orlistat (Xenical) contraindications - ANSWER Malabsorption syndrome and cholestasis
, Lorcaserin (Belviq) - ANSWER weight loss drug
Lorcaserin adverse effects - ANSWER HA, back pain, decrease lymphocytes and URIs, hypoglycemia
in diabetics
Lorcaserin adverse reactions that are less common - ANSWER Blood dye radios, cognitive
impairment, psychiatric disorders, priapism, HTN, valvular heart disease
Weight loss drugscontraindications for children - ANSWER Not recommended.
- orlistat is not approved for kids under 12
Diethylpropion and phentermine are not for children under 16
Weight loss drugs contradictions: pregnancy - ANSWER Not recommended
Can take diethylpropion- it's not teratogen; but neonates born to women who take this drug May
experience withdrawal
Weight loss drugs contradictions: breastfeeding - ANSWER Not recommended for all drugs
Weight loss drugs for older adults contradictions - ANSWER Those with renal impairment
-Naltrexone/bupropion should be limited to one tablet daily
- creatinine level is less than 50
-phentermine/topiramate should be limited to 7.5/46 capsule daily
-lorcaserin should not be given with 30 or less creatinine clearance
Nalrexone (ReVia) - ANSWER Decrease the ability opioid analgesics to relieve pain
-do not take within 2 weeks of a MAOI
Orlistat (Xenical) drug interactions - ANSWER Levothyroxine- may cause hypothyroidism by
decreasing the absorption of thyroid hormone. If drug is needed take them 4 hrs apart
-cyclosporine- can reduce absorption, give them 2-3 hrs apart
Baseline data: Liraglutide - ANSWER HB A1C, lipids, renal function
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