NUR 311 Final Exam Study Guide with Questions and Complete Solutions
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Course
NUR 311
Institution
NUR 311
How do drugs affect the elderly? many drugs are metabolized slowly, have a longer action and are more likely to accumulate
What are patient related variables to drug absorption and action? age, weight, the individual drug response (pharmacogenetics), ethnicity, sex
What are drug related variables...
NUR 311 Final Exam Study Guide with
Questions and Complete Solutions
How do drugs affect the elderly? ✅many drugs are metabolized slowly, have a longer
action and are more likely to accumulate
What are patient related variables to drug absorption and action? ✅age, weight, the
individual drug response (pharmacogenetics), ethnicity, sex
What are drug related variables to drug absorption and action? ✅dosage, route of
admin, drug-diet interactions, drug-drug interactions
four components of pharmacokinetics ✅1. Absorption
2. Distribution
3. Metabolism
4. Excretion
A type of warning that appears in a drug's prescribing information and is required by the
U.S. Food and Drug Administration (FDA) to alert prescribers of serious adverse events
that have occurred with the given drug ✅black box warning
The ___________ enforces the controlled substances act ✅DEA
The most severe adverse effect of HMG-CoA reductase inhibitors (statins)
✅rhabdomyolysis
____________ can injure muscle tissue, resulting in muscle pain, weakness and aches
✅statins
adverse effects of HMG-CoA reductase inhibitors (statins) ✅nausea
constipation
diarrhea
abd cramps
headache
mechanism of action of cholestyramine (bile acid sequestrant) ✅binds to bile acids on
the intestinal lumen, causing the bile acids to be excreted in the feces
Use of cholestyramine (bile acid sequestrant) ✅used as a *combination drug* to
reduce LDL cholesterol
, T/F cholestyramine (bile acid sequestrant) is used as monotherapy for the treatment of
elevated cholesterol ✅false; used in combo with fibrates of statins
patients receiving warfarin concurrently with ___________ require substantially
decreased dosage of warfarin because they displace warfarin from binding sites on
serum albumin (increases the risk for bleeding) ✅fibrates
T/F fibrates and statins can be given concurrently for the treatment of high cholesterol
✅false; the use of these two medications concurrently increases the change of
rhabdomyolysis
when taking antidiabetics and ___________ concurrently, the risk for hypoglycemia
increases ✅fenofibrate
Adverse effects of nitrogylcerin ✅Headache
Orthostatic hypotension
syncope
Tolerance
brady/tachy
contraindications to nitroglycerin ✅severe anemia
hypotension
hypovolemia
S/S of acetaminophen toxicity ✅n/v
anorexia
jaundice
delirium --> coma
contraindications to ibuprofen ✅pregnancy
kidney failure
PUD
bleeding/anemia
pre op for CABG
Black box warning: _____________ is contraindicated for the treatment of periop pain
after CABG ✅ibuprofen
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