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BCH 361 Chapter 18 Questions Study Questions with 100% Correct Verified Solutions| Latest Update $9.99   Add to cart

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BCH 361 Chapter 18 Questions Study Questions with 100% Correct Verified Solutions| Latest Update

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Assume that in a cell the ratio listed is high. Which ratio(s) would lead to a decrease in the rate of entrance of acetyl CoA into the citric acid cycle? - Answer NADH/NAD+ Which of the following statements is TRUE regarding the mechanism of pyruvate dehydrogenase complex? - Answer A carbanion i...

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BCH 361 Chapter 18 Questions Study Questions
with 100% Correct Verified Solutions| Latest
Update
Assume that in a cell the ratio listed is high. Which ratio(s) would lead to a decrease in
the rate of entrance of acetyl CoA into the citric acid cycle? - Answer NADH/NAD+


Which of the following statements is TRUE regarding the mechanism of pyruvate
dehydrogenase complex? - Answer A carbanion is formed on TPP following the release
of H+


The blue lysine side chain shown here is part of the structure of: - Answer dihydrolipoyl
transacetylase


Although symptoms of beriberi are similar to those seen with mercury exposure,
beriberi affects the _____ subunit of pyruvate dehydrogenase complex, while mercury
exposure affects the _____ subunit. - Answer E1; E3


A mutant pyruvate dehydrogenase complex is generated in the lab in which the
lipoamide is linked to the amide backbone group of E2 directly at a similar location as
the wild-type enzyme. Which of the following statements is likely TRUE of such a
mutant? - Answer The mutant will initially be able to decarboxylate pyruvate, but the
reaction will not proceed past this point


The protein environment of dihydrolipoyl dehydrogenase is important in the function of
the complex because it: - Answer increases the electron-transfer potential of FAD


Beriberi involves a reduction in the activity of pyruvate dehydrogenase complex. Which
enzyme(s) in the complex is/are specifically affected in this disease through loss or
reduction of a prosthetic group? - Answer pyruvate dehydrogenase component (E1)

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