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Exam (elaborations)

ABSITE GI Questions and Answers

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The most common presenting symptoms of colorectal cancer patients under 40  :-- Rectal bleeding Which of the following causes secretin release from the duodenal mucosa  :-- The most common oncogene abnormality observed in association with colorectal cancer is ?  :-- Amplification of ...

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  • August 28, 2024
  • 23
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • ABSITE
  • ABSITE
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Apluss
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Elscores: Aug. 27, 24- 2024/2025

ABSITE GI Questions and Answers
The most common presenting symptoms of colorectal cancer patients under 40


 :-- Rectal bleeding




Which of the following causes secretin release from the duodenal mucosa


 :--




The most common oncogene abnormality observed in association with colorectal cancer is ?


 :-- Amplification of the K-ras oncogene




What is Rovsing sign


 :-- Pain in the right lower quadrant induced by palpation in the left lower quadrant.




What is it iliopsoas sign


 :-- Most often seen with a retrocecal appendix, pain elicited by extension of the right hip




Crohn disease is associated with a number of extraintestinal manifestations. Extraintestinal

problems not affected by therapy for intestinal disease include:


 :-- Ankylosing spondylitis and primary sclerosing cholangitis do not correlate with bowel

disease activity, and thus the clinical course is not attenuated by surgical resection of

intestinal Crohn disease.




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, 2
Elscores: Aug. 27, 24- 2024/2025

Appendiceal carcinoid, Indication for right hemicolectomy


 :-- Tumors greater than 2 cm, tumors found at the base of the appendix




Recurrent episodes of sigmoid colonic diverticulitis prompt operative therapy. Which of the

following describes the appropriate margins for resection?


 :-- Proximal margin, descending colon; distal margin, upper rectum




Neoadjuvant combined chemotherapy and radiation therapy in rectal cancer


 :-- decreases local recurrence rates when compared with postoperative radiation therapy




Ingested calcium is primarily absorbed in the


 :-- Once in its ionized form, calcium is primarily absorbed in the duodenum, although

this process occurs throughout the length of the small intestine.




The migrating motor complex of the small intestine


 :-- Motilin is thought to be the primary gut hormone responsible for regulating migrating

motor complex.




Most of the carcinoid tumors which produce the malignant carcinoid syndrome originate in the




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, 3
Elscores: Aug. 27, 24- 2024/2025

 :-- ileum,While more carcinoid tumors occur in the appendix, the tendency of

appendiceal carcinoids to metastasize is low (~3%) while ileal carcinoids metastasize

about 35%of the time, making it much more likely to have carcinoid syndrome of ileal

origin from metastatic disease.




Location of carcinoid


 :-- more than 90% of carcinoids are found in three sites—appendix (~45%), ileum

(~30%), and rectum (~15%).




modified Astler-Coller system


 :-- Stage A represents tumors that invade into the mucosa only.

Stage B1 tumors invade into but not through the muscularis propria.

Stage B2 lesions invade through the bowel wall without adjacent organ involvement

Stage B3 tumors involve adjacent organs.

Stage C tumors involve regional lymph nodes and are subgrouped into stages C1, C2, and C3,

according to depth of bowel-wall penetration.

Stage D represents evidence of distant organ involvement.

the 5-year survival rate among patients with

stage D disease is less than 10%.

stages A, B, and C are 90%, 77%, and 47%, respectively.

stage C disease, the number of positive nodes is an

important predictor of survival.


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