COMPLETE BOC ASCP PREP
QUESTIONS AND ANSWERS
1) Following overnight fasting, hypoglycemia in adults is
defined as a glucose of:
a. <70 mg/dL (<3.9 mmol/L)
b. <60 mg/dL (<3.3mmol/L)
c. <55 mg/dL (<3.0mmol/L)
d. <45mg/dL (<2.5mmol/L) AN...
1) Following overnight fasting, hypoglycemia in adults is
defined as a glucose of:
a. <70 mg/dL (<3.9 mmol/L)
b. <60 mg/dL (<3.3mmol/L)
c. <55 mg/dL (<3.0mmol/L)
d. <45mg/dL (<2.5mmol/L) ANSWER d (Diagnosis of
hypoglycemia in adults.)
3) The preparation of a patient for standard glucose tolerance
testing should include:
a. a high carbohydrate diet for 3 days
b. a low carbohydrate diet for 3 days
c. fasting for 48 hrs. prior to testing
d. bed rest for 3 days ANSWER a (GTT diet preparation.)
4) If a fasting glucose was 90 mg/dL, which of the following 2
hr. postprandial glucose result would most closely represent
normal glucose metabolism?
a. 55 mg/dL (3.0 mmol/L)
b. 100 mg/dL (5.5 mmol/L)
c. 180 mg/dL (9.9 mmol/L)
d. 260 mg/dL (14.3 mmol/L) ANSWER b (Normal 2 hour
postprandial value.)
,5) A healthy person with a blood glucose of 80 mg/dL (4.4
mmol/L) would have a simultaneously determined
cerebrospinal fluid glucose value of:
a. 25 mg/dL (1.4 mmol/L)
b. 50 mg/dL (2.3 mmol/L)
c. 100 mg/dL (5.5 mmol/L)
d. 150 mg/dL (8.3 mmol/L) ANSWER b (Ratio of CSF glucose
to blood glucose)
6) A 25 yr. old man became nauseated and vomited 90 mins
after receiving a standard 75 g carbohydrate dose for an oral
glucose tolerance test. The best course of action is to:
a. give the patient a glass of orange juice and continue the test
b. start the test over immediately with a 50 g carbohydrate dose
c. draw blood for glucose and discontinue the test
d. place the patient in a recumbent position, reassure him and
continue the test. ANSWER c (Use of partial GTT information.)
7) Cerebrospinal fluid for glucose assay should be:
a. refrigerated
b. analyzed immediately
c. heated to 56C
d. stored at room temperature after centrifugation ANSWER b
(Effect of glycolysis on glucose.)
8) Which of the following 2 hr. postprandial glucose values
demonstrates unequivocal hyperglycemia diagnostic for
diabetes mellitus?
a. 160 mg/dL (8.8 mmol/L)
b. 170 mg/dL (9.4 mmol/L)
c. 180 mg/dL (9.9 mmol/L)
d. 200 mg/dL (11.0 mmol/L) ANSWER d (Unequivocal
diagnosis of diabetes mellitus.)
10) A 45 yr. old woman has a fasting serum glucose
concentration of 95 mg/dL (5.2 mmol/L) and a 2 hr.
postprandial glucose concentration of 105 mg/dL (5.8 mmol/L).
,The statement which best describes this patient's fasting serum
glucose concentration is:
a. normal; reflecting glycogen breakdown by the liver
b. normal; reflecting glycogen breakdown by skeletal muscle
c. abnormal; indication diabetes mellitus
d. abnormal; indicating hypoglycemia ANSWER a (Factors
contributing to PBS.)
9) Serum levels that define hypoglycemia in pre-term or low
birth weight infants are:
a. the same as adults
b. lower than adults
c. the same as a normal full-term infant
d. higher than a normal full-term infant ANSWER b (Age effect
on glucose.)
11) Pregnant women with symptoms of thirst, frequent urination
or unexplained weight loos should have which of the following
tests performed?
a. tolbutamide test
b. lactose tolerance test
c. epinephrine tolerance test
d. glucose tolerance test ANSWER d (Gestational diabetes.)
12) In the fasting state, the arterial and capillary blood glucose
concentration varies from the venous glucose concentration by
approximately how many mg/dL (mmol/L)
a. 1 mg/dL (0.05 mmol/L)
b. 5 mg/dL (0.27 mmol/L)
c. 10 mg/dL (0.55 mmol/L)
d. 15 mg/dL (0.82 mmol/L) ANSWER b (Arterial vs venous
glucose values.)
13) The conversion of glucose or other hexoses into lactate or
pyruvate is called:
a. glycogenesis
b. glycogenolysis
, c. gluconeogenesis
d. glycolysis ANSWER d (Definition of glycolysis)
14) Which of the following values obtained during a glucose
tolerance test are diagnostic of diabetes mellitus?
a. 2 hr. specimen = 150 mg/dL (8.3 mmol/L)
b. fasting plasma glucose = 126 mg/dL (6.9 mmol/L)
c. fasting plasma glucose = 110 mg/dL (6.1 mmol/L)
d. 2 hr. specimen = 180 mg/dL (9.9 mmol/L) ANSWER b
(Diagnosis of diabetes mellitus)
15) The glycated hemoglobin value represents the integrated
values of glucose concentration during the preceding:
a. 1-3 weeks
b. 4-5 weeks
c. 6-8 weeks
d. 16-20 weeks ANSWER c (Definition of glycated hemoglobin.)
16) Monitoring long term glucose control in patients with adult
onset diabetes mellitus can best be accomplished by
measuring:
a. weekly fasting 7 am serum glucose
b. glucose tolerance testing
c. 2 hr. postprandial serum glucose
d. hemoglobin A1c ANSWER d (Average glucose over time is
best predictor.)
18) Total glycosylated hemoglobin levels in a hemolysate
reflect the:
a. average blood glucose levels of the past 2-3 months
b. average blood glucose levels for the past week
c. blood glucose level at the time the sample is drawn
d. hemoglobin A1c level at the time the sample is drawn
ANSWER a (Interpretation of glycated hemoglobin.)
19) Which of the following hemoglobins has glucose-6-
phosphate on the amino-terminal valine of the beta chain?
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