Exam (elaborations)
PHM 350 Exam #4 Questions With Complete Solutions
- Course
- Institution
PHM 350 Exam #4 Questions With Complete Solutions
[Show more]
Content preview
PHM 350 Exam #4 Questions With Complete Solutions1st Generation Cephalosporins Correct Answers Cefazolin,
Cephalexin
- G+ and minimal G- activity
- very sensitve to penicillinase
- used when allergy to penicillin or prophylactic prior to surgery
2nd Generation Cephalosporin Correct Answers Cefoxitin
- increased effect in G-
- increased entry to CNS
- increased resistance to penicillinase
- used when allergy to penicillin or prophylactic prior to surgery
30S Inhibitor Drugs Correct Answers Tetracyclines (MDDT),
Aminoglycosides (SKNGT), Linezoid
30S Inhibitor: Aminoglycosides Correct Answers
Streptomycin, Kanamycin, Neomycin, Gentamycin, Tobramycin
30S Inhibitor: Linezoid [Mechanism of Action, Spectrum of
Action, Restrictions] Correct Answers Mechanism of Action
- bind and inhibit 30S
- bactericidal
- developed in response to increased resistance of G+ to
antibiotics like penicillin, vancomycin, cephalosporins
Spectrum of Action
- G+
Restrictions
,- undocumented, new drug
30S Inhibitors: Tetracyclines Correct Answers Minocycline,
Doxycycline, Demeclocycline, Tetracycline
3rd Generation Cephalosporin Correct Answers Cefotaxamine
- increase G+ and G- effectiveness
- increased resistance to penicillinase
- increased entry to CNS
- used for salmonella, meningitis, some nosocomial infections
4th Generation Cephalosporin Correct Answers Cefepime
- increased resistance to penicillinase
- increased spectrum of action
- increased entry to CNS
- used for salmonella, meningitis, some nosocomial infections
5-fluorouracil [Mechanism of Action] Correct Answers -
Antimetabolite
- Substitute for U (precursor of T)
- Produces abnormal DNA
- Failure of cell replication
- Failure of protein production = cell death
50S Inhibitors Correct Answers Erythromycin, Clindamycin
5th Generation Cephalosporins Correct Answers Ceftaroline,
Ceftobiprole
- increased absorption in GI
- increased resistance to penicillinase
- increased entry to CNS
, - Used to treat MRSA infections
6-mercaptopurine, Thioguanine [Mechanism of Action] Correct
Answers - Antimetabolites
- Substitute A and G in DNA
- Produces abnormal DNA
- Failure of cell replication
- Failure of protein production = cell death
Acetaminophen (Mechanism of Action and Uses) Correct
Answers Mechanism of Action
- block COX1 and COX2, prevent AA binding to enzyme
Uses
- Analgesic
- Antipyretic
- Substitute for hypersensitivity to aspirin
Alkylating Agent: Cisplatin [Mechanism of Action] Correct
Answers - Categorized under alkylating agents, but it doesn't
alkylate DNA
- Binds and cross links DNA
- inhibits DNA synthesis, protein synthesis, and cell replication
- Dose-limiting Side effect: Renal toxicity (can be prevented by
proper hydration]
Alkylating Agents Correct Answers Lomustine,
Mechlorethamine, Cyclophosphamide, Chlorambucil,
Carmustine (Nitrogen Mustards)
Cisplatin, Mitomycin
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Classroom. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
81298 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now
