Exam (elaborations)
UTA PHARMACOLOGY Chapter 2 Pharmacologic Principles (solved 2024)
- Course
- Institution
UTA PHARMACOLOGY Chapter 2 Pharmacologic Principles (solved 2024)
[Show more]
Content preview
UTA PHARMACOLOGYChapter 2
Pharmacologic
Principles (solved
2024)
What is Pharmacology - answer The study of drugs and
their interaction with
living systems
• A drug is any chemical substance other
than those normally required (food/water)
which affects living systems by changing their
structure or function
• Clinical pharmacology - the study of drugs in
humans
Subsections of Pharmacology
Pharmacokinetcs
• Pharmacodynamics
• Pharmaco-therapeutics
• Pharmaco-genomics
,• Pharmaco-economics-
• Pharmaco-ethnography - answer Pharmacoknetics-is
how the body responds to the drug
Pharmocotherapeutics- using drugs to for diagnoses and
help cure diseases
Phamaco-genomics- are the variations in interactions wiht
drus and all genes
Pharmaco-economics- sociatal factors that affect the
ability to get a drug(like income)
Pharmacoethnography- the cultural or ethnic background
that affects how one doesnt take a drug(religous belief) or
reacts to a drug i.e. pharmogenetic or genetic
polymorphism
Pharmacogenetics and
Pharmacogenomics - answer The way an individual's
geneFc inheritance
contributes to how they respond to drugs
• Usually a single nucleotide difference in a given
population
- *Genetic polymorphisms*
- *Affect the Cytochrome P450 enzyme system*and some
drug receptors
• Drugs that are commonly involved:
pain meds; antidepressants;antihypertensives;
asthma meds; cancer drugs; and many more
Drug Polymorphisms - answer *Genetic polymorphisms*
, • *effect the pharmacokinetics of specific drugs or drug
classes due to:
• varying expression of the particular *CYP450 enzyme
family that metabolizes the drug*.
- May affect a drug target (receptor) *
- Genetic poly morphisms interact with: a person's
inherited genetic variation, and /or environmental
factors that cause changes to DNA outside the
nucleus (epigenetics) to determine the treatment
outcome (effect) of a pharmacologic agent.
• We can now test for some of these variants
Patient Adherence to Drug Therapy factors - answer - Age
- Education level
- Severity of illness
- Understanding of the importance of toxicity
- Length and complexity of therapy
- Symptom abatement
- Cultural beliefs
- Side effects
- Cost
Pharmacologic Principles Pharmocokinetics and
Pharmacodynamics - answer Pharmacokinetics
• Pharmacon (drug / poison) Kinetics(movement)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller BRAINBOOSTERS. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $15.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75759 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now