A 60-year-old female presents with persistent fatigue, night sweats, and painless swelling of cervical lymph nodes. Laboratory tests show an elevated LDH level. A lymph node biopsy reveals a diffuse large B-cell lymphoma. What is the most appropriate next diagnostic test to further characterize the...
ONC Study Revision Questions with Correct
Answers
A 60-year-old female presents with persistent fatigue,
night sweats, and painless swelling of cervical lymph
nodes. Laboratory tests show an elevated LDH level. A
lymph node biopsy reveals a diffuse large B-cell
lymphoma. What is the most appropriate next diagnostic
test to further characterize the extent of the disease?
A) Bone Marrow Biopsy
B) Chest X-ray
C) PET-CT Scan
D) Lumbar Puncture
C) PET-CT Scan
Lumbar puncture → if sinus, testicular, orbital, epidural,
or BM involvement (wouldn't be the next best step)
A 55-year-old female is diagnosed with non-Hodgkin's
lymphoma, and the oncologist plans the staging of the
disease. What system is commonly used for staging non-
Hodgkin's lymphoma?
A) Rai & Binet Staging
B) Lugano classification
,C) TNM staging
D) Bloom-Richardson grading
B) Lugano classification
→ it's a type of Ann Arbor so if Ann Arbor is an opt &
Lugano isn't...
A 45-year-old male is diagnosed with non-Hodgkin's
lymphoma (NHL). What is the most likely subtype of non-
Hodgkin's lymphoma?
A) Follicular Lymphoma
B) Diffuse Large B-cell Lymphoma
C) Mantle Cell Lymphoma
D) Burkitt Lymphoma
B) Diffuse Large B-cell Lymphoma
aka Intermediate
Which of the following is categorized as indolent non-
Hodgkin's lymphoma?
A) Diffuse Large B-cell Lymphoma
B) Follicular Lymphoma
,C) Acute lymphoblastic leukemia
D) Burkitt Lymphoma
B) Follicular Lymphoma
Which of the following is categorized as intermediate
non-Hodgkin's lymphoma?
A) Diffuse Large B-cell Lymphoma
B) Follicular Lymphoma
C) Acute lymphoblastic leukemia
D) Burkitt Lymphoma
A) Diffuse Large B-cell Lymphoma
Which of the following is categorized as aggressive non-
Hodgkin's lymphoma?
A) Follicular Lymphoma
B) Mantle Cell Lymphoma
C) Burkitt Lymphoma
D) Chronic Lymphocytic Leukemia (CLL)
C) Burkitt Lymphoma
, --> aggressive, but highly curable cool cool
A 25-year-old male with known HIV infection presents
with rapidly growing jaw and facial masses, along with
abdominal pain and distension. Biopsy reveals a starry-
sky appearance with medium-sized, monomorphic
lymphocytes. What is the most likely diagnosis?
A) Diffuse Large B-cell Lymphoma
B) Follicular Lymphoma
C) Burkitt Lymphoma
D) Mantle Cell Lymphoma
C) Burkitt Lymphoma
A 55-year-old female presents with persistent, itchy, and
scaly patches on her skin. Biopsy results reveal abnormal
T cells infiltrating the skin. Considering the cutaneous
involvement, what is the most common form of
cutaneous T-cell lymphoma?
A) Mycosis Fungoides
B) Sezary Syndrome
C) Anaplastic Large Cell Lymphoma
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