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NUR3145 Immunity Exam Latest Update
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NUR3145 Immunity Exam Latest Update ...
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NUR3145 Immunity Exam Latest Updatemethotrexate - Answer wkly low dose + supplemental folic acid
SE: bone marrow suppression
if either partner isn't pregnant
non-biologic DMARDs - Answer methotrexate & leflunomide
leflunomide - Answer DMARD
alters immune syst response
higher incidence of SE than methotrexate
SE: bone marrow suppression + rash, elevated LFTs, diarrhea, HTN, fatigue
DMARDs - Answer disease-modifying antirheumatic drugs
disease-modifying antirheumatic drugs - Answer drugs that reduce the progression and
tissue destruction of the inflammatory disease process by inhibiting tumor necrosis
factor
biologic DMARDs - Answer used if unresponsive no non-biologic, genetically engineered
to block cytokines (for immunity)
risk for infection
ex: etanercept, abatacept, tofacitinib
biologic response modifiers (BRM) - Answer hematopoietic agents & monoclonal
antibodies
used to slow disease progression
produced by normal cells, they repair, stimulate, or enhance substances within the
immune system to kill cancer cells.
hematopoietic agent - Answer BRM that stimulates bone marrow to gen blood parts
colony-stimulating factors: granulocytes
monoclonal antibodies - Answer BRM
targets specific cells in an autoimmune disease
type 1 interferons - Answer reduce cytokine & immune cells : immunomodulating
property
anti-interleukin 6 receptor antibody - Answer block inflammation in autoimmune diease
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