UOfT Physiology - SCS 2159 - Lecture 09 -
Neuro 06 Exam Study Guide
How many neurons and synapses in the CNS? - Answer 100 billion (10^11) neurons, 100
trillion (10^14) synapses.
Neuroglia compose (?)% of the CNS - Answer 75-90%
Subarachnoid Space - Answer Shock absorbing space filled with cerebrospinal fluid
(CSF)
CSF - Answer Cerebrospinal fluid, a clear, watery fluid, similar to plasma, cushions
brain and maintains a stable interstitial fluid environment.
Volume of CSF in adults - Answer 125mL-*150mL*.
Composition of CSF compared to plasma - Answer Less proteins, glucose and *K+*.
More sodium and chloride.
CSF circulation - Answer 1. CSF is secreted by ependymal cells of the choroid plexus
(Mostly in lateral ventricles).
2. CSF flows from lateral ventricles and 3rd ventricle through the cerebral aqueduct into
the 4th ventricle.
3. CSF in 4th ventricle flows into subarachnoid space by passing through openings in
the roof of the 4th ventricle. These openings are the paired lateral apertures and the
single median aperture. CSF also fills the central canal of the spinal cord.
4. As it travels through the subarachnoid space, CSF removes waste products and
provides buoyancy for the brain and spinal cord.
5. CSF is recycled when reabsorbed by arachnoid villi. It exits the subarachnoid space
and enters the bloodstream.
Blood-Brain Barrier - Answer Special anatomy within the subarachnoid space consisting
of capillaries with tight junctions that block the passage of larger substances that aren't
actively transported.
Astrocytes eliminate those substances that were "denied entry".
Dermatome - Answer Sensory area of skin supplied by a single spinal nerve
Function of dorsal grey matter - Answer Dorsal horn. Sensory function (*remember*)
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