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pharm exam 1 NUR 2060 (2
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pharm exam 1 NUR 2060 (2
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pharm exam 1 NUR 2060_________________ is more effective when used with dexamethasone (a steroid med) -
ANS-serotonin receptor antagonist
ADR's of weight loss drugs - ANS-decreases fat soluble vitamins and beta-carotene; may
decrease absorption of thyroid hormone replacement,
antibiotics to eradicate H. pylori - ANS--amoxicillin (Amoxil)
-bismuth (Pepto Bismil)
-metronidazole (Flagyl)
anticholinergic example - ANS-scopolamine (Transderm scop)
anticholinergic uses and effects - ANS-nausea, vomiting, motion sicknes
-effects: blurred vision, dry mouth, drowsiness, urinary retention, constipation
Antihistimine uses - ANS-motion sickness and vertigo symptoms of vertigo
bismuth subsalicylate - ANS--gastric cytoprotectant: possess topical mucosal effects
-antimicrobial effects: binds to bacterial toxins
-is an NSAID (risk for reyes syndrome in infants)
bismuth subsalicylate uses - ANS--H. pylori infection (adults and children)
-diarrhea (ages 12 and older)
-traveler's diarrhea propylaxis
butyrophenone use - ANS-antagonizes dopamine & alpha receptors
can a REMS drug be given to any patient? - ANS-no, only patients in certain healthcare
settings, e.g. hospitals or physician's offices.
-only dispensed to patients with specific documentation showing they're approved
-patients are subject to monitoring
cannabinoids: - ANS--bind to cannabinoid receptors
-are second line due to unpleasant temporal effects and dependence potential
-can be used to stimulate appetite
causes of acute diarrhea - ANS--infection (e. Coli and c. Dif)
-GI disease
-change in diet
-nervousness and anxiety
, -allergic rxn
-intoxication
-side effect of medication
causes of chronic diarrhea - ANS--related to disease or disorder
-malabsorption syndrome
-inflammatory bowel disease
-endocrine disorder
chloride channel activator action - ANS-promotes secretion of chloride into the bowel by
activating chloride channels and enhance motility and fluid secretion in small intestine
semisoft stool in 24 hours
potential teratogen
chloride channel activator example - ANS-lubiprostone (Amitiza)
does cardiac output increase or decrease with aging? - ANS-decreases
-decreased arterial elasticity
does every drug need REMS? - ANS-no
dopamine antagonist example - ANS-metoclopramide (Reglan)
dopamine antagonist uses - ANS-antagonizes dopamine, stimulates GI tract mobility (pro-kinetic
subclass)
during which weeks are fetuses most at risk for physical malformations? - ANS-weeks 3-8
-teratogen exposure during this period
during which weeks are fetuses most at risk for physiological malformations? - ANS-weeks
9-term
histamine H2 receptor antagonist examples - ANS--cimetidine (Tagamet)
-ranitidine (Zantac)
-famotidine (Pepcid)
IBS medications - ANS--dicyclomine (Bentyl)- decreases GI motility, antichollinergic, good for
cramps and abdominal pain
-alostetron (Lotronex)- only for women with severe diarrhea inducing IBS, REMS program used
with this
-lubiprostone (Amitiza)- chloride channel activator for constipating IBS
indications of chloride channel activator - ANS-chronic idiopathic constipation
constipating irritatable bowel syndrome
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