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Immunology Kuby - Exam 1.

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Immunology Kuby - Exam 1.

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  • June 3, 2024
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  • 2023/2024
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Immunology Kuby - Exam 1
*CD4+ T cells* recognize antigen presented on: - ANS-*Class II MHC on APCs*

*Develops receptors* that are highly tailored to each pathogen - ANS-*Adaptive
immunity*

*Immune responses are initiated* in the ___ lymphoid organs. - ANS-*Secondary*

*Responds identically* to first and second exposure of the same antigen - ANS-*Innate
immunity*

*Signal transduction through the BCR depends on a complex* called: - ANS-*IgA and
IgB*

*Utilizes PRRs* - ANS-*Innate immunity*

All blood cells in an adult human *originally begin* in which compartment within the
body? - ANS-*Bone marrow*

An *ITAM* is best described as a tyrosine motif found on ____. - ANS-*Intracellular
signaling proteins and cytoplasmic tails of some receptors that become phosphorylated
upon ligand-receptor engagement*

Antibodies are composed of - ANS-*Two identical heavy chains and two identical light
chains*

Cytokines in this family can *stimulate chemotaxis* - ANS-*Chemokine family*

Important in *cell lineage differentiation from hematopoietic stem cells* -
ANS-*Hematopoietin family*

In mammals, *T-cell maturation occurs in the ___, while B-cell maturation occurs
predominantly in the ___* - ANS-*Thymus; bone marrow*

In the bone marrow, *less mature cells would be found* in the _______ niche. -
ANS-*Endosteal*

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