a "dry tap" bone marrow aspiration may be seen with what chronic myeloid proliferative disease?
A: essential thrombocythemia
B: polycythemia vera
C: primary myelofibrosis
D: Chronic myeloid leukemia correct answers Primary myelofibrosis
what clinical feature is more often associated with e...
MMSC 433 Exam 3 Questions (100% Accurate)
a "dry tap" bone marrow aspiration may be seen with what chronic myeloid proliferative disease?
A: essential thrombocythemia
B: polycythemia vera
C: primary myelofibrosis
D: Chronic myeloid leukemia correct answers Primary myelofibrosis
what clinical feature is more often associated with essential thrombocythemia than with the other
chronic myeloproliferative disorders?
A: bleeding and thrombosis
B: infections
C: splenomegaly
D: fatigue correct answers bleeding and thromboses
what is the most common chromosomal abnormality in polycythemia vera (PV)?
A: BCR-ABL
B: PML-RARA
C: TET-2
D: JAK2V617F correct answers JAK2V617F
which of the following is an expected finding in polycythemia vera?
A: normal white cell count
B: anemia
C: increased RBC mass
D: low leukocyte alkaline phosphatase correct answers increased RBC mass
a patient has a normal white cell count, a moderately high platelet count, and mild anemia. The differential shows immature granulocytes, nucleated red cells, and teardrop-shaped red cells. Which of the following is most likely?
A: chronic myelogenous leukoemia
B: primary myelofibrosis
C: polycythemia vera
D: essential thrombocythemia correct answers primary myelofibrosis
a patient has a platelet count of 1200*10 /L. Many platelets are giant and have abnormal shapes. ⁹
A mild anemia is present. The bone marrow has increased megakaryocytes in clusters; iron stores are present. Which of the following is most likely?
A: chronic myelogenous leukemia B: polycythemia vera
C: thrombosis secondary to blood loss
D: essential thrombocythemia correct answers essential thrombocythemia
which one of the following chromosome abnormalities is associated with CML?
A: t(8;14)
B: trisomy 18
C: t(15;17)
D: t(9;22) correct answers t(9;22)
all of the following are minor criteria for overt PMF, except:
A: WBC count < 10*10 /L ⁹
B: palpable splenomegaly
C: leukoerythroblastosis
D: leukocytosis ≥ 11*10 /L correct answers WBC count < 10*10 /L ⁹ ⁹
what is the treatment for Polycythemia Vera (PV)?
A: therapeutic phlebotomy
B: ruxolitinib (inhibitor of JAK2)
C: hydroxyurea
D: all answers are correct correct answers all answers are correct
hematopoietic stem cell transplantation is accepted as a cure for MDS
A: true
B: false correct answers true
in which chronic myeloid proliferative disorder is the leukocyte alkaline phosphatase (LAP) score decreased?
A: PV
B: CML
C: ET
D: PMF correct answers CML
A patient has a platelet count of 700 x 10 /L with abnormalities in size, shape, and granularity of ⁹
platelets; a WBC count of 12 x 10 /L; and hgb of 11 g/dL. The Philadelphia chromosome is not ⁹
present. The most likely diagnosis is:
A. PV
B. ET
C. Leukemoid reaction
D. CML correct answers ET
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